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Journal of Case Reports
Non-Hodgkin’s Lymphoma of Spleen: A Rare Site of Primary Presentation
Manishi Bansal1, Smriti Gupta2, Girdhar Gopal3, Ankush Jindal4
Departments of 1Radiotherapy, 2Pathology and 3Oncosurgery, Mayo Hospital, Mohali; 4Government Medical College and Hospital, Chandigarh, India.
Corresponding Author:
Dr. Manishi Bansal
Email: manishi1@yahoo.com
Received: 13-MAY-2020 Accepted: 13-JUL-2020 Published Online: 30-JUL-2020
DOI: http://dx.doi.org/10.17659/01.2020.0041
Background: Isolated splenic involvement in non-Hodgkin’s lymphoma is a rare clinical entity and is termed as primary splenic lymphoma (PSL). In such cases, the disease is mostly confined to spleen and splenic hilar lymph nodes. It usually presents with dragging pain in left side of abdomen and huge splenomegaly is detected on investigations. Splenectomy is the main modality of treatment followed by chemotherapy with or without radiation. Case Report: We present a rare case of PSL treated successfully at our institution with splenectomy and chemotherapy. Conclusion: Primary splenic lymphoma is a rare splenic neoplasm. Immunohistochemistry markers are helpful in confirming the diagnosis. Splenectomy is both diagnostic and therapeutic in such cases. 
Keywords : Primary Splenic Lymphoma, Non-Hodgkin’s Lymphoma, Splenectomy, Splenic radiation, Diffuse Large B-cell Lymphoma.
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