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Journal of Case Reports
Ovarian Metastasis as Initial Presentation of Primary Thyroid Carcinoma: A Case Report and Review of Literature
Debadrita Ray1, Amar Ranjan1, Harshita Dubey1, Arka De2, Chitresh Kumar1
1Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi. 2Post Graduate Institute of Medical Education & Research, Chandigarh, India.
Corresponding Author:
Dr Debadrita Ray
Email: raydebadrita1690@gmail.com
Received: 07-JUL-2020 Accepted: 14-AUG-2020 Published Online: 20-SEP-2020
DOI: http://dx.doi.org/10.17659/01.2020.0051
Introduction: Ovarian metastases from thyroid carcinoma are rare. It needs to be differentiated from malignancy occurring in the setting of struma ovarii as the management and prognosis of the two conditions are different. Case Report: A 50-year old lady presented with gradually increasing lower abdominal and low-back pain. Abdominal examination revealed a mass in the left lower quadrant. Histopathology examination of the resected thyroid specimen showed poorly differentiated thyroid carcinoma with immunoreactivity for CK7 and TTF1 but not for CK20, Napsin or WT1. The patient received paclitaxel and carboplatin followed by palliative radiotherapy and I131 therapy. Conclusion: Ovarian metastases from thyroid carcinoma may pose a diagnostic dilemma. Histopathology and immunohistochemical studies are crucial in establishing the diagnosis and management planning.
Keywords : Biopsy, Immunohistochemistry, Ovarian Neoplasms, Struma Ovarii, Thyroid Neoplasms.
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