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Journal of Case Reports
Myeloid Sarcoma: A Masquerade
Shweta Rathi, Poonam Panjwani, Anuradha Ananthamurthy, Pritilata Rout
Department of Pathology, St. John’s Medical College, Sarjapur Road, Kormangala, Bangalore, India.
Corresponding Author:
Dr Shweta Rathi
Email: drshwetamantri12@gmail.com
Received: 06-SEP-2020 Accepted: 27-OCT-2020 Published Online: 30-NOV-2020
DOI: http://dx.doi.org/10.17659/01.2020.0065
Background: Myeloid sarcoma (MS) may occur de novo, precede or coincide with acute myeloid leukemia (AML) but its presentation as the initial manifestation is rare. Case Report: We present a series of six cases of myeloid sarcoma in an age group ranging from 15 to 62 years, involving paraspinal area, lymph node, ileum and appendix. Three cases had a prior diagnosis of AML and in the rest, a diagnosis of myeloid sarcoma preceded further investigations which did not reveal any other site of involvement. Conclusion: The diagnosis of myeloid sarcoma is important especially in patients who do not have associated hematologic abnormalities at presentation. Immunohistochemistry is an invaluable tool that assists in arriving at a correct diagnosis. 
Keywords : Acute Myeloid Leukemia, Immunohistochemistry, Lymph Nodes, Myeloid Sarcoma, Soft Tissue Neoplasms.
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