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Journal of Case Reports
Polypoidal Metastatic Leiomyosarcoma Diffusely Involving the Gastrointestinal Tract
Anuradha Sekaran1, Supraja Sukumar1, Rohini Muriki2, Rakesh Kalapala2, Sundeep Lakhtakia2, Duvvur Nageshwar Reddy2
Departments of 1Pathology and 2Medical Gastroenterology, AIG Hospitals, Hyderabad, Telangana, India.
Corresponding Author:
Dr. Anuradha Sekaran
Email: dr.sanuradha@aighospitals.com
Received: 28-JUL-2020 Accepted: 24-NOV-2020 Published Online: 15-DEC-2020
DOI: http://dx.doi.org/10.17659/01.2020.0068
Background: Retroperitoneal leiomyosarcoma, a malignant neoplasm with smooth muscle differentiation, seldom metastasize. The gastrointestinal tract is rare site of metastases, and diffuse polypoidal involvement is an uncommon presentation. Case Report: A 61-year-old male diagnosed with retroperitoneal leiomyosarcoma underwent surgical resection of the tumor along with chemotherapy and radiation. He presented with 2 months history of vomiting, and melena. Upper gastrointestinal (GI) endoscopy, capsule endoscopy and colonoscopy revealed numerous polypoidal lesions throughout the gastrointestinal tract, suspicious of a GI polyposis syndrome. Histopathology, including immunohistochemistry, confirmed metastatic leiomyosarcoma. Conclusion: Diffuse polypoidal lesions in the gastrointestinal tract presenting as metastases from a retroperitoneal leiomyosarcoma are extremely rare.
Keywords : Colonoscopy, Endoscopy, Gastrointestinal Neoplasms, Melena, Retroperitoneal Leiomyosarcomas.
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