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Primary Mediastinal Germ Cell Tumors
Caroline E. Lippe, Troy Moritz
General Surgery Program, UPMC Pinnacle Community Osteopathic, 4300 Londonderry Road, Harrisburg, PA 17109, United States.
Corresponding Author:
Dr. Caroline E. Lippe
Email: caroline.e.lippe@gmail.com
Received:
17-JUL-2020
Accepted:
2-OCT-2020
Published Online:
20-DEC-2020
DOI:
http://dx.doi.org/10.17659/01.2020.0069
Abstract
Background
: Primary malignant mediastinal germ cell tumors (PMMGCT) are exceedingly rare, accounting for 1-2% of germ cell tumors. The objective of this case report is to highlight the severity and unique characteristics of this tumor.
Case Report
: A young, active 33 year old male presented to a community emergency department with flu-like symptoms and hemoptysis continuously for one month. Work-up noted a large anterior mediastinal mass with erosion into the sternum. Biopsy revealed a non-seminomatous germ cell tumor, with primary malignant origin in the mediastinum. Chemotherapy was initiated, which the patient has tolerated well during his first few rounds of treatment.
Conclusion
: PMMGCTs are rare and aggressive tumors with variable response to chemotherapy. Extensive surgery has been offered for those with resistant factors, with more complications.
Keywords :
Biopsy, Germ Cell and Embryonal Neoplasms, Mediastinal Neoplasms, Nonseminomatous germ cell tumor, Neoplasms.
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