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Journal of Case Reports
Sclerosing Polycystic Adenosis of Salivary Gland: A Newly Described Tumor with Review of Literature
Shweta Rathi, Wasim Selimul Haque, Vinita Pant, Anita Borges 
SRL Diagnostics, Centre of Excellence, Histopathology, Mahim, Mumbai, Maharashtra, India.
Corresponding Author:
Dr Shweta Rathi
Email: drshwetamantri12@gmail.com
Received: 05-NOV-2020 Accepted: 24-DEC-2020 Published Online: 28-FEB-2021
DOI: http://dx.doi.org/10.17659/01.2021.0012
Background: Sclerosing polycystic adenosis (SPA) is a rare, recently described, tumorous condition of the major or minor salivary glands that on gross and microscopic evaluation mimics an invasive carcinoma. The histology is quite similar to that seen in fibrocystic disease, sclerosing adenosis and adenosis tumors of the breast. It also resembles the more diffuse and bilaterally occurring polycystic dysgenetic disease (PDD) of the parotid gland. To the best of our knowledge, only 68 cases have been described so far. Case Report: Here we describe a case of SPA involving the parotid gland in a 58 year old male. At the first instance, the possibility of a low grade mucoepidermoid carcinoma was considered. However, histologically, it was a well circumscribed lobulated lesion composed of acini and ducts in a sclerotic stroma. Immuno-staining for SMA and p63 highlighted the myoepithelial cells around the ducts and acini which exhibited extensive metaplastic changes. Conclusion: Awareness of SPA is essential to avoid misdiagnosis with other common malignant salivary gland tumors and thus prevent its overtreatment.
Keywords : Diagnostic Errors, Hyperplasia, Mucoepidermoid Carcinoma, Parotid Gland, Salivary Gland Neoplasms.
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