Background: Giant ovarian cystadenomas represent a severe condition, only rarely reported in literature. Usually, patients suffering of this condition undergo surgery, given the potential risk of malignancy as well as bulky symptoms. Case Report: Here we report 69-year-old female with a rapidly-grown giant ovarian mass. As suggested by the pre-operative CT-scan, bilateral ureteral stent (J-J) was placed before surgery, followed by laparotomy with hysterectomy and bilateral salpingo-oophorectomy. Histopathological examination showed that this giant mass was a borderline ovarian serous cystadenoma. During the post-operative course the patient had a minor nephrological complication related to J-J, which was resolved within 48 hours, the patient was discharged at 8 days post-surgery. Conclusion: Here we show that a multidisciplinary team might crucially help in treating this challenging condition, which usually hide unexpected pitfalls.