Background: Coma is defined as lack of both awareness and response to external stimulation. Psychogenic coma is unresponsiveness without organic causes, it described in DSM IV as dissociative disorder NOS. Case Report: This case report is first psychogenic coma in older adult with major depressive disorder reported in Oman. Conclusion: Management of a coma due to dissociative disorder NOS is largely supportive. Principles include speaking to the patient in a calm reassuring manner and avoiding repeated painful stimuli with close monitoring of vital signs.