Background: Primary tubercular liver abscess is a rare presentation of tuberculosis. Case Report: We report on a 38-year-old lady who developed a tubercular abscess of liver without pulmonary involvement. Ultrasound and computed tomography of abdomen showed evidence of liver abscess. Subsequent percutaneous aspiration of the abscess demonstrated acid fast bacilli. Treatment with anti-tubercular drugs improved her symptoms and resolved the liver abscess. Conclusion: Tuberculosis should be suspected in pyrexia of unknown origin with liver abscess in endemic areas after other infective sources are excluded.