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Journal of Case Reports
Pleuroparenchymal Fibroelastosis following Asbestos Exposure
Neha Bipin Patel1, Timothy Patrick McCann1, David William Wiltse2
Departments of 1Internal Medicine and 2Pulmonary Medicine, Good Samaritan Hospital, Cincinnati, OH, United States.
Corresponding Author:
Dr Neha Bipin Patel 
Email: neha_patel@trihealth.com
Received: 16-FEB-2022 Accepted: 16-OCT-2022 Published Online: 05-NOV-2022
DOI: http://dx.doi.org/10.17659/01.2022.0029
Background: Pleuroparenchymal fibroelastosis is considered a rare form of interstitial lung disease. There are a growing number of case reports, however no large-scale studies detailing both clinical and histopathological features along with long term follow-up. An association with asbestos exposure has been described however this too has been limited to a few case reports. Case Report: A 73-year-old man with a history of interstitial lung disease and asbestos exposure presented with dyspnea with biopsy and imaging suggestive of pleuroparenchymal fibroelastosis. Despite steroid and anti-fibrotic therapy, the disease advanced rapidly causing the patient and family to pursue palliative care. Conclusion: Asbestos exposure is a significant risk factor for pleuroparenchymal fibroelastosis, a rare but increasingly recognized entity. Biopsy and image findings are the mainstay of diagnosis, pulmonary function tests are useful in prognostication. Treatment is supportive. 
Keywords : Acute Respiratory Distress Syndrome, Asbestosis, Interstitial Lung Disease, Pulmonary Fibrosis, Diffuse Parenchymal Lung Disease.
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