Background: COVID-19, caused by SARS-CoV-2, presents with diverse manifestations, including both respiratory and non-respiratory symptoms, which can vary among individual patients. Case Report: We present a case of a 54-year-old male with a history of diabetes and hypertension who contracted COVID-19. Interestingly, he exhibited no respiratory symptoms despite testing positive for the virus. The patient had recently returned from a seven-day trip to Porto de Galinhas (PE) with his wife. He initially experienced myalgia, arthralgia, fever, and loss of appetite, but did not exhibit any respiratory manifestations. Conclusion: This case highlights that COVID-19 can manifest without respiratory symptoms and affect other systems in the body. It underscores the importance of considering non-respiratory symptoms in the diagnosis and management of COVID-19 cases.