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Journal of Case Reports
Isolated Diplopia as the Sole Manifestation of Solitary Clival Plasmacytoma
Hari Kiran G1, Nigel P Symss1, Bhanu K2
Departments of 1Neurosurgery and Spine disorders and 2Pathology, Gleneagles Global Health City, Chennai, India.
Corresponding Author:
Dr Hari Kiran G
Email: harikiran75@gmail.com
Received: 29-DEC-2023 Accepted: 11-OCT-2024 Published Online: 15-APR-2025
DOI: http://dx.doi.org/10.17659/01.2025.0009
Abstract
Background: Plasmacytomas are monoclonal proliferations of plasma cells occurring in bone or soft tissue without systemic involvement. Solitary bone plasmacytoma (SBP) is a localized tumor without other skeletal lesions or bone marrow infiltration. Clival involvement is extremely rare, with few cases reported. Case Report: A 47-year-old male presented with a 3-month history of diplopia. MRI revealed a T1- and T2-isointense clival lesion with bone destruction. Endoscopic transnasal transsphenoidal biopsy confirmed plasmacytoma. Systemic workup ruled out multiple myeloma. The patient received 50 Gy radiotherapy in 25 fractions. At 14-month follow-up, he showed complete clinical recovery and reduction in tumor size. Conclusion: Solitary clival plasmacytoma is a rare but treatable cause of isolated diplopia. It should be considered in the differential diagnosis of clival lesions, with radiotherapy offering favourable outcomes.
Keywords : Chemotherapy, Diplopia, Plasmacytoma, Radiotherapy, Tumor.
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