Background: Follicular cholecystitis is a rare variant of chronic cholecystitis which is often missed or misdiagnosed on imaging. It is defined as at least three lymphoid follicles per cm of gallbladder (GB) tissue with an inflammatory infiltrate composed almost exclusively of scattered, well-formed lymphoid follicles. Case Report: The present case was preoperatively diagnosed as chronic cholecystitis, as the patient presented with similar symptoms. Ultrasonography indicated a thickened gallbladder wall with a single stone. Gross examination revealed a denuded mucosal lining and thickening of the wall. Microscopic analysis showed numerous lymphoid follicles, some with germinal center formation, leading to a histopathological diagnosis of follicular cholecystitis. Conclusion: Follicular cholecystitis (FC) is a rare benign gallbladder condition that can be challenging to diagnose, often resembling lymphoma. Accurate diagnosis requires careful histopathological examination and immunohistochemical (IHC) analysis.