Striae distensae are common innocuous skin lesions. We report a patient of nephrotic syndrome with corticosteroid-induced large striae, which suddenly developed bulging and fluid accumulation. There were no associated cutaneous or systemic symptoms. Analysis of aspirated fluid showed it was a transudate and culture was sterile. It was concluded that edema fluid, as part of anasarca, had preferentially accumulated within the striae, probably due to their altered dermal mechanical properties. Recognizing this entity is important to avoid unnecessary alarm or irrational use of antibiotics.