Duplication cysts are rare congenital anomaly of gastrointestinal tract. Majority of them present in early infancy, with bleeding or intestinal obstruction. The commonest location of these cysts is ileum. However, ileo-cecal duplications are extremely rare. Presented herein is a case of an infant with acute intestinal obstruction due to ileo-cecal duplication cyst. The clinical and radiological signs were similar to more commonly seen intussusception and diagnosis was established intraoperatively.