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Diagnostic Dilemma of Polymorphous Low Grade Adenocarcinoma of Hard Palate
Seema Monga, Junaid Nasim Malik, Arun Parkash Sharma, Sujata Jetley
Department of Otorhinolaryngology and Head & Neck Surgery, HIMSR & HAHC Hospital, Jamia Hamdard University, Delhi-110062, India.
Corresponding Author:
Dr. Seema Monga
Email: dr.seema.monga@gmail.com
Received:
28-DEC-2013
Accepted:
10-FEB-2014
Published Online:
10-MAR-2014
DOI:
http://dx.doi.org/10.17659/01.2014.0023
Abstract
Polymorphous low grade adenocarcinoma (PLGA) is an indolent malignant tumor affecting the minor salivary gland almost exclusively. It is important to differentiate PLGA from other salivary gland tumors with myoepithelial differentiation such as pleomorphic adenoma and adenoid cystic carcinoma.We report a case of a 55 year old male who presented with an asymptomatic swelling on the hard palate for the past one year. FNAC of the swelling was suggestive of pleomorphic adenoma and surgical excision with adequate margins was done. Histopathological and immunohistochemistry examination of the excised specimen came out to be PLGA. A very inquisitive work up including adequate sized biopsy and immunohistochemistry is recommended for the diagnosis of PLGA. The clinician and the cytopathologist should be aware of the characteristic cytomorphologic and immunohistochemistry features of PLGA to distinguish it from pleomorphic adenoma as happened in the present case.
Keywords :
Salivary Gland Neoplasms, Adenoma, Pleomorphic, Adenoid Cystic Carcinoma, Immunohistochemistry, Hard Palate.
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Malik JN
Sharma AP
Jetley S
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