Transient bacteraemia following surgical procedures is a relatively common, but concomitant infective endocarditis in patient without any risk factor is a rare event. To the best of our knowledge, this is one of the few case reports of infective endocarditis following a urology procedure. We report a 57-year-old lady with pyelonephritis and renal calculus who developed vegetation’s on chordae tendinae following renal surgery.