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Journal of Case Reports
Renal Leiomyosarcoma – A Rare Entity

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Suresh Babu1, Atin Singhai1, Nuzhat Hussain2, Vishwajeet Singh3 
From the Department of Pathology1 and Urology3, King George’s Medical University, Lucknow; Department of Pathology2, RML Institute of Medical Sciences, Lucknow, India. 
Corresponding Author:
Dr. Atin Singhai
Email: atinsinghai@yahoo.com
Received: 04-DEC-2013 Accepted: 12-JAN-2014 Published Online: 20-JAN-2014
DOI: http://dx.doi.org/10.17659/01.2014.0008
Abstract
Primary sarcomas constitute only 1-2% of malignant renal tumours in adulthood and of these leiomyosarcomas account for 50-60%. We describe here a case of renal leiomyosarcoma in an elderly woman, presenting with abdominal lump, anorexia and weight loss for 3 months. Based on CECT abdomen findings, a presumptive differential diagnosis of sarcomatoid variant of renal cell carcinoma/ renal sarcoma was made. Microscopy reflected a malignant spindle cell neoplasm which showed strong reactivity for smooth muscle actin with negative epithelial markers, thereby confirming the diagnosis of renal leiomyosarcoma. To conclude the entity of renal sarcoma should be taken in to consideration while evaluating renal tumours, particularly in older females, owing to their aggressive nature and low survival rates. 
Keywords : Leiomyosarcoma, Kidney neoplasms, Sarcoma, Anorexia, Weight loss, Diagnosis.
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