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Journal of Case Reports
Successful Management of High Grade Myxofibrosarcoma of the Forearm

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Abdellatif El Bahraouy1, Mohamed Réda Khmamouche2, Mohamed Oukabli3, Tarik El Yaacoubi1, Youssef Benyass1, Bouchaib Chafry1, Salim  Bouabid1, Driss Benchebba1, Abderrahmane Albouzidi3, Belkacem Chagar1
Departments of Traumatologic-Orthopedic1, Medical Oncology2 and Anatomical Pathology3; Military Hospital MOHAMED V, Rabat, Morocco.
Corresponding Author:
Dr. Abdellatif El Bahraouy
Email: abdellatifelbahraouy@gmail.com 
Received: 18-OCT-2015 Accepted: 26-APR-2016 Published Online: 15-JUN-2016
DOI: http://dx.doi.org/10.17659/01.2016.0064
Abstract
Myxofibrosarcoma  or myxoid variant of malignant fibrous histiocytoma (MFH) is one of the most common sarcomas in the extremities  in adults and particularly in elderly patients. It is characterized by a high frequency of local recurrence. We report a patient with high grade myxofibrosarcoma infiltrating the striated muscle of the right forearm. On microscopic examination, the tumor lacked areas of necrosis and pronounced cellular pleomorphism. Immunohistochemically, the tumor cells showed intense reactivity to S-100 protein (PS 100) and discrete reactivity of desmin, CD34 and SMA. After surgery of the tumor, the patient received local radiotherapy and chemotherapy. One year after treatment, the patient has been alive without  local recurrence or distant metastasis. 
Keywords : Forearm, Histiocytoma, Humans, Necrosis, Neoplasm Recurrence.
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