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Journal of Case Reports
Immature Testicular Teratoma Post-operatively Presenting as Chemotherapy Resistant Retroperitoneal Mature Teratoma
Saravanakumari Vijayakumar1, Bhawana Ashok Bade1, Debashish Gochait1, Sreerag KS2
Department of 1Pathology and 2Urology, JIPMER, Pondicherry-605006, India.
Corresponding Author:
Dr. Saravanakumari Vijayakumar
Email: sarakumari15@gmail.com
Received: 15-MAR-2016 Accepted: 18-JUN-2016 Published Online: 25-AUG-2016
DOI: http://dx.doi.org/10.17659/01.2016.0096
Abstract
Introduction: Growing teratoma syndrome (GTS), first described in 1982, presents as newly growing metastatic masses in patients previously treated for immature teratoma. Since 1994, only 13 cases have been reported in India. Case Report: A 21 year old male who had undergone orchidectomy for immature teratoma presented with retroperitoneal mass 6 months later. He received 4 cycles bleomycin-etoposide-cisplatin based chemotherapy without change in size of mass. He underwent excision of tumor and retroperitoneal lymph nodes. Histopathology revealed mature teratoma predominantly cartilage, respiratory and enteric epithelium and adipose tissue without immature elements.  Conclusion: These tumors cause adjacent vascular and organ invasion causing compressive symptoms. GTS mimics tumor recurrence and patients need to be on regular follow up for detecting these tumors, for they are resistant to chemoradiotherapy and are amenable to surgical resection.
Keywords : Abdominal Pain, Bleomycin, Nephrectomy, Teratoma, Testicular Neoplasms.
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