Kounis syndrome is the coincidental occurrence of acute coronary syndromes with allergic or hypersensitivity reactions. Kounis syndrome has been established as a hypersensitivity coronary disorder induced by various conditions, drugs, environmental exposures, food items and drug eluting coronary stents. It is not a rare disease but an infrequently diagnosed clinical entity. Clinicians should be aware that various mediators of allergy can cause coronary spasm and even plaque rupture and thrombus formation, thereby causing a serious impact on the course, prognosis and management of the allergic reaction. Here we report a rare case of Type 1 Kounis syndrome triggered by nordrenaline in a patient with pyogenic meningitis.