Gangrene involving the whole upper limb is generally uncommon. When seen, it usually affects parts of the upper limb and is usually as a result of mismanagement of fractures by traditional bone setters (TBS). We present the case of a 2 year old girl with gangrene of the upper limb as a result of inadvertent ligation of the axillary vessels. Lack of recognition of the error and delayed presentation to a specialist center contributed to irreversible damage to the limb. Prompt resuscitation, excision of gangrenous limb and post-operative care were indispensable in the excellent outcome achieved.