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Journal of Case Reports
A Rare Variant of Postpartum Diabetes Insipidus
Rajeshwari Janakiraman1, Karthik Rao2, Megha N Shalavadi3, Chenna Keshava BG3  
Departments of 1Endocrinology and 2Critical Care, Columbia Asia Referral Hospital, Yeshwanthpur, Bengaluru; Department of 3Critical Care, MS Ramaiah Memorial Hospital, Bengaluru, Karnataka, India.
Corresponding Author:
Dr. Chenna Keshava BG
Email: ckeshava7@gmail.com
Received: 17-JUN-2016 Accepted: 25-AUG-2016 Published Online: 10-NOV-2016
DOI: http://dx.doi.org/10.17659/01.2016.0127
Abstract
Transient diabetes insipidus (DI) is an uncommon pregnancy-related condition which results from the excessive placental vasopressinase activity. Imaging of brain usually reveals hyper-intense signal in posterior pituitary gland. Extrapontine myelinolysis with elevated creatinine phosphokinase (CPK) secondary to hypernatremia of gestational diabetes insipidus as seen in our patient, is rarely reported. This case report describes remarkable improvement in a 28 year old primigravida who presented with gait disturbance with elevated CPK and high sodium.
Keywords : Diabetes Insipidus, Hypernatremia, Postpartum Period, Pregnancy, Sodium.
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