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Journal of Case Reports
High CA – 125 in Patients with Endometrioma
Deepika Taneja, Sadhna Gupta, Anita Bansal
Department of Obstetrics and Gynaecology, Maharaja Agrasen Hospital, West Punjabi Bagh, New Delhi 110026, India.
Corresponding Author:
Dr. Deepika Taneja 
Email: deepikaa1988@gmail.com
Received: 24-SEP-2016 Accepted: 20-FEB-2017 Published Online: 15-MAR-2017
DOI: http://dx.doi.org/10.17659/01.2017.0027
Background: Increased CA-125 concentrations are seen during ovulation and menstruation. It is produced from endometrium and irritation of peritoneum (by infection/surgery/endometriosis). High plasma levels of more than 200 U/mL are usually suggestive of malignancy but rarely found in benign conditions of female genital tract, like endometriosis. Case Report: Two patients with abdominal mass and suspected diagnosis of ovarian malignancy presented with high levels of CA-125. In the first case, endometrioma excision was done with unilateral salpingoophorectomy The second case was treated by hysterectomy with bilateral salpingoophorectomy. A fall in CA-125 levels was observed in both cases, and no recurrence was reported on follow up. Conclusion: Endometrioma should be suspected in adnexal mass with high CA-125, even in the absence of widespread endometriosis.
Keywords : Biopsy, Endometriosis, Laparotomy, Neoplasm Recurrence, Omentum.
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