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Journal of Case Reports
MR Parkinsonism Index in Progressive Supranuclear Palsy
Sunil Bhatt1, Sunil Jee Bhat1, Priyanka Vikas Kashyap2, Vandana Prasad1
Departments of 1Internal Medicine and 2Neurology, Shri Guru Ram Rai Institute of Medical and Health Sciences and Shri Mahant Indiresh Hospital, Dehradun, Uttrakhand, India.
Corresponding Author:
Dr. Priyanka V Kashyap
Email: dr_pvinod@yahoo.co.in
Received: 22-NOV-2016 Accepted: 16-JAN-2017 Published Online: 05-FEB-2017
DOI: http://dx.doi.org/10.17659/01.2017.0014
Abstract
Background: Progressive supranuclear palsy (PSP) is a neurodegenerative disease characterized by dystonic rigidity of the neck and axial muscles, frequent falls, supranuclear vertical gaze palsy and pseudo-bulbar palsy. There is neuronal loss in the tegmentum of the midbrain leading to its significant atrophy along with changes in substantia nigra, globus pallidus and red nucleus. Case Report: Here we are presenting specific MRI features of PSP in an elderly male with special note on humming bird sign and MR parkinsonism index which is very useful to correctly label the diagnosis of PSP in absence of pathological confirmation. Conclusion: Specific methods are needed for diagnosing PSP as the clinical differentiation of PSP from Parkinson disease (PD) and multiple-system atrophy of Parkinson type (MSA-P) may be difficult in early stages. Emphasis on utility of MRI brain in PSP has been proven especially when mid-sagittal sections are studied.
Keywords : Atrophy, Bulbar Palsy, Multiple System Atrophy, Parkinson Disease, Supranuclear Palsy.
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