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Journal of Case Reports
Osteitis Fibrosa Cystica of Tibia as Initial Manifestation of Primary Hyperparathyroidism
Shushan Shweta Jayker, Chippagi Jyothi Prakash, Manjunatha Yedatore Arkeswara, Mohammed Naushad Ansari, Shingati Muhammed Hashim, Parthasarathi Achappa
Department of Pathology, Rajarajeswari Medical College and Hospital, Kambipura, Mysore road, Bangalore-560074, Karnataka, India. 
Corresponding Author:
Dr. Shushan Shweta Jayker
Email: shwetajayker@gmail.com
Received: 22-JUL-2016 Accepted: 29-NOV-2016 Published Online: 05-JAN-2017
DOI: http://dx.doi.org/10.17659/01.2017.0001
Abstract
Background: Primary hyperparathyroidism is disease of excessive secretion of parathyroid hormone. Osteitis fibrosa cystica or brown tumor, complication of primary hyperthyroidism is characterized by fibrotic cystic bony changes.  Skeletal manifestations in the form of brown tumors are rare  occuring in less than 2% of patients suffering from any form of hyperparathyroidism. Case Report: We report a 40-year-old woman with lytic lesions in tibia, diagnosed as osteitis fibrosa cystica secondary to parathyroid adenoma. Conclusion: Patients with primary hyperparathyroidism are usually asymptomatic and clinical presentation of the lesion in tibia is rarely a first sign of the disease. 
Keywords : Neoplasms, Osteitis Fibrosa Cystica, Parathyroid Hormone, Primary Hyperparathyroidism, Tibia.
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