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Journal of Case Reports
Primary Laryngeal Amyloidoma: A Rare Entity
Amarnath Raghavendra1, Nagarajan Murugaiyan1, Banu Ramesh1, Basha Mahfooz2
Departments of 1Radiation Oncology and 2Pathology, Valavadi Narayanasamy Cancer Centre, G. Kuppuswamy Naidu Memorial Hospital, Coimbatore 641037, Tamil Nadu, India.
Corresponding Author:
Dr. Nagarajan Murugaiyan 
Email: mnr81@yahoo.com
Received: 05-JUN-2018 Accepted: 29-OCT-2018 Published Online: 10-NOV-2018
DOI: http://dx.doi.org/10.17659/01.2018.0069
Background: Primary laryngeal amyloidosis is a rare lesion accounting for 0.2-1.2% of benign tumors of larynx. Case Report: A 60 year old female presented with complaints of hoarseness of voice. On evaluation MRI neck showed an ill defined mass lesion measuring 15.2 x 6.2 mm in the false cord. Histologically Congo red stain highlighted amyloid deposit and characteristic apple green birefringence was present. Systemic amyloidosis was ruled out. Thus a diagnosis of localized amyloidoma of larynx was made. Patient underwent endoscopic resection of the lesion. Conclusion: Laryngeal amyloidoma is rare disorder of localized amyloidosis. Systemic involvement should be ruled out. The diagnosis should be confirmed histologically. Surgical resection is the mainstay of treatment.
Keywords : Amyloidosis, Congo Red, Hoarseness, Larynx, Laryngeal Diseases.
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