Background: As renal transplants are increasing day by day, we often encounter ever more complications associated with it. Transplant renal artery stenosis (TRAS) has been considered as one of the most important and preventable vascular complication of renal transplantation. It may develop earlier or later after renal transplantation and both may develop with different etiology and patho-physiology. Currently, percutaneous trans-luminal angioplasty (PTA) with stenting has been considered as most favorable and successful option for managing TRAS. Case Report: Here in present case series, we represent two such cases of different patients: i) a 34-year-old woman successfully underwent PTA. After four months of renal transplant, she developed 80-90% stenosis of recipient internal iliac artery, and ii) a 15-year-old boy underwent PTA after 10 days of renal transplant for discrete lesion of donor vessel near anastomotic site. Conclusion: TRAS can manifest with the varied presentations and can be treated successfully with timely interventions.