Background: Tuberculosis (TB) is one of the top ten causes of death worldwide. Chest wall tuberculosis is not infrequently encountered in endemic areas although it is rare. Clinically it resembles pyogenic abscess or benign soft tissue tumors, making the diagnosis difficult particularly in the absence of warning signs. Case Report: A 45 year old male presented with gradually enlarging soft tissue mass in the right upper anterior thoracic wall. Fine needle aspiration suggested chronic granulomatous disease, histopathology confirmed chest wall tuberculosis. Patient responded to anti-tubercular therapy and surgery. Conclusion: Anti-tubercular treatment and adjunctive surgery are quite effective in chest wall tubercular cases.