Background: Common variable immunodeficiency (CVID) is an immune disorder characterized by recurrent infections, low antibody levels and varied presentations. Case Report: We present a case of common variable immune deficiency (CVID) which is a rare disorder and is characterized by recurrent bacterial infections in adults. Our patient had been suffering from recurrent skin and soft tissue infections and pneumonia since five years. He was diagnosed with CVID and started intravenous immunoglobulins. He has been stable with improved quality of life since discharge. Conclusion: A strong index of suspicion in patients presenting with recurrent skin-soft tissue and sino-pulmonary infections leading to timely diagnosis and treatment of CVID can be rewarding.