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Journal of Case Reports
Ectopic Thyroid Tissue in the Lung

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Tugba Özbek1, Nesibe Kahraman Çetin1, Nilgün Kuman Kanlioglu2, Serdar Sen2, Ibrahim Halil Erdogdu1, Ibrahim Meteoglu1
Department of Pathology1 and Thoracic Surgery2, Adnan Menderes University, Medical School, Aydin, 09100, Turkey.
Corresponding Author:
Dr. Ibrahim Meteoglu
Email: imeteoglu@hotmail.com
Received: 01-MAR-2016 Accepted: 16-MAY-2016 Published Online: 15-JUL-2016
DOI: http://dx.doi.org/10.17659/01.2016.0079
Abstract
The result of dismigration during organogenesis, thyroid gland can rarely present outside their usual anatomical localization, especially midline cervical, thoracic and abdominal cavity. The lung is a rare localization for ectopic thyroid tissue. Most patients are asymptomatic. However, they can be noticeable as a solitary pulmonary nodule, during tests conducted for other purposes, or during autopsy. A 47-year-old female patient presented with chest pain for 3 months. She had a past history of subtotal thyroidectomy for nodular goitre 31 years ago. Computed tomography showed anterobazal segment nodule in right lower lobe of lung. After thoracotomy, dirty yellow, solid nodular lesion, 1 cm in diameter, was observed in lung wedge resection material. Histological examination showed the lesion was separated with a sharp boundaries from the lung parenchyma, had non-teratogenic components, and thyroid tissue was found with a colloid-containing follicular structures. Immunohistochemical staining showed TTF-1 and thyroglobulin expression in this area. With these findings the patient was diagnosed as ectopic thyroid tissue. We want to emphasize that although it is rare, ectopic thyroid tissue can be localized intrapulmonary, and this should be considered in the differential diagnosis of pulmonary nodules.
Keywords : Solitary Pulmonary Nodule, Thyroglobulin, Thyroid Dysgenesis, Thyroidectomy, Tomography.
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