Background: Pineoblastoma are rare and aggressive tumors with only few studies evaluating the therapeutic strategies on this condition. Hence we report a case of pineoblastoma in an adult patient treated with cranio-spinal irradiation (CSI) and chemotherapy following surgery. Case Report: A  27 year old female presented with double vision associated with headache. MRI brain showed a heterogenous enhancing polypoidal mass lesion in the posterior aspect of third ventricle. She underwent gross total excision of the lesion. Post-operative histopathological examination was consistent with pineoblastoma (grade IV). She was treated with CSI and concurrent chemotherapy. Conclusion: The treatment for adults with pineoblastoma consists of surgery followed by craniospinal radiotherapy with or without addition of chemotherapy.