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Journal of Case Reports
Leptomeningeal Carcinomatosis Secondary to Undifferentiated Sinonasal Carcinoma
Agrata Sharma1, Aniketh Hegde2, Ujjawal Khurana2, Jitendra Sinha2
Departments of 1Neurology and 2Pathology, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India.
Corresponding Author:
Dr Agrata Sharma
Email: dragrata@gmail.com
Received: 30-JUN-2026 Accepted: 29-JUL-2026 Published Online: 25-AUG-2026
DOI: http://dx.doi.org/10.17659/01.2026.0015
Abstract
Background: Sinonasal carcinoma is a rare and aggressive malignancy, with leptomeningeal carcinomatosis being an uncommon presentation. Case Report: We report a rare case of leptomeningeal carcinomatosis secondary to undifferentiated sinonasal carcinoma in a patient presenting with paraparesis. CSF analysis revealed atypical cells, and MRI demonstrated diffuse nodular leptomeningeal enhancement. Conclusion: A high index of suspicion is essential for diagnosing leptomeningeal carcinomatosis in patients with sinonasal carcinoma presenting with neurological deficits.
Keywords : Carcinoma, Leptomeningeal Carcinomatosis, MRI, Paraparesis, Paranasal Sinus Neoplasms.
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